You’ve probably tried it at least once. Perhaps more often. It went well for a while, and then it slowly crept back. And somewhere a little voice whispered: I just don’t have enough willpower.

Today I want to tell you something different, and I promise you: no miracle cure, no guilt, and only what the science genuinely shows. Because the truth is more honest — and more reassuring — than the diet industry would have you believe. We’ll look at why your body fights back, what changes at each stage of life (including why losing weight in menopause feels so much harder), and what the research says actually works in a way you can keep up.

1. The unfair truth: your body fights back

Picture your body as a house with a thermostat. Not for temperature, but for weight. Scientists call this the set point: a weight your body has come to regard as “normal” and defends tooth and nail.

Eat less, and that system notices less energy is coming in — and it reacts as though famine is looming. Two things happen at once:

  • Your burn drops more than you’d expect from your weight alone. This is called adaptive thermogenesis: your body learns to “do more with less.”
  • Your hunger hormones ramp up. The satiety hormone leptin falls, the hunger hormone ghrelin rises. You feel hungrier, and food becomes more appealing.

And here comes the sobering part: in a well-known study, these hormonal changes were still present at least a year after the weight loss. So your body keeps pushing you for months to win back that lost weight. That’s why a large proportion of people who lose weight see it return within a few years.

Read that paragraph again, and let this sink in: regaining weight is not a weakness of character. It’s biology. That realisation isn’t an excuse to give up — it’s the beginning of an approach that doesn’t fight your body, but works with it.

2. “My metabolism has stalled” — what’s true and what isn’t

Almost everyone says it: from thirty onwards, or after menopause, my metabolism just stalled. It feels true. But the largest study to date tells a surprisingly different story.

In 2021, researchers analysed the energy expenditure of more than 6,400 people, from babies to 95-year-olds. What did they find? Once you correct for body size and muscle mass, your burn is remarkably stable between the ages of 20 and 60. Only after about 60 does it slowly begin to decline, by less than one per cent a year. And the analysis found no separate effect of the menopause on the metabolic rate.

So how can it be that so many people still gain weight around that age? The answer isn’t a metabolism that “collapses,” but quieter shifts: we slowly lose muscle mass, we often move less, we sleep worse, and life gets busier. It’s those things together — not a broken engine — that make the difference.

That’s good news. Because there’s nothing you can do about a “broken metabolism.” But you can do something about muscle, movement and sleep.

A focused woman looking at her reflection after an intense workout

3. Why age and life stage do matter after all

The metabolism may be stable, but your body at fifty isn’t the same as at twenty. Here it differs by group.

Young adults (roughly 20–35). This is where the body is at its most supple. Losing weight often goes relatively smoothly — but this is precisely where the habits that stay with you for life are formed. The pitfall isn’t your body, but building patterns on crash diets you can’t keep up later.

Middle age (men and women). It’s not your metabolism but your life that changes: desk work, busyness, less movement, poorer sleep. It creeps on by a few hundred grams a year. Men more often gain it around the belly, women more around the hips and thighs — until menopause shifts that pattern.

Women in menopause. For many this is the hardest chapter, and it genuinely is harder — just not for the reason you often hear. It’s not that your metabolism suddenly stalls. What happens is this: the fall in the hormone oestrogen causes fat to move to the belly (so-called visceral fat, around your organs), speeds up the loss of muscle mass, makes your body less sensitive to insulin, and often disrupts your sleep. Less muscle means you burn slightly less at rest. Poorer sleep disrupts your hunger hormones. And here comes a surprising, honest nuance from the large SWAN study: at the onset of menopause, fat gain doubles and muscle mass declines, while the rate at which your total weight rises doesn’t even accelerate. In other words: the number on the scales need not change dramatically, but your shape does — and losing weight feels like swimming against the current. That’s not imagination and not a lack of discipline; it’s your changing body. What helps most against this, according to research: preserving muscle (strength training), enough protein, and taking sleep seriously.

Older adults (60+). Now the metabolism really does decline, slowly. At the same time, muscle loss accelerates (sarcopenia). The goal shifts subtly here: not so much “losing weight,” but preserving muscle and strength, so you stay strong and independent. Protein and strength training become more important still.

4. So which diet is best? (An honest answer)

This is the one everyone wants the answer to. Low carb? Low fat? Keto? And the honest summary of the best research is almost disappointingly simple.

In a carefully designed study of more than 600 people, a healthy low-carbohydrate diet was compared head to head with a healthy low-fat diet, for a whole year. The result: no meaningful difference in weight loss. And — strikingly — not even someone’s genes or insulin response predicted which diet worked better for whom.

What did count in that same study was not which camp you chose, but two other things: the quality of what you ate (less ultra-processed, more real food) and — more important still — how well you kept it up.

That may be the single most important sentence in this whole article: the best diet isn’t a particular diet. It’s the diet you can keep up. All diets work through the same dial — a modest energy deficit — and they all fail at the same point: the moment you can no longer sustain them.

5. Intermittent fasting: hype or help?

Intermittent fasting (for example, eating only within an eight-hour window) is enormously popular. The big promise: you burn more, or in some special way. What does the research say?

When you set intermittent fasting alongside ordinary daily calorie restriction, the results in meta-analyses are virtually equal. The differences that exist are small and not clinically meaningful — a picture that recurs across dozens of randomised studies and in large overview analyses pooling hundreds of trials. In other words: fasting is no magic. It works for the people it works for, because a shorter eating window helps them eat less of their own accord — so again: via an energy deficit.

For some people that’s a wonderful tool: fewer decisions, a clear rhythm. For others it leads instead to overeating or an unhealthy relationship with food. One point to note from the research: with fasting you can lose muscle as well as fat, so protein and strength training remain important. It’s a tool in the box — not the golden key.

6. What the science does consistently say

Once you filter out all the noise, a surprisingly calm, honest picture remains. None of the points below sells a product — and that’s precisely why I trust them:

  • An energy deficit is the common denominator. How you reach it (fewer carbs, less fat, an eating window) makes little difference to your weight.
  • Sustaining it is the real skill. Choose the approach that fits your life, not an influencer’s.
  • Protect your muscles. Strength training and enough protein ensure you lose fat instead of muscle — at any age, and especially in and after menopause.
  • Sleep and stress count. Poor sleep throws your hunger hormones off balance. It’s no side issue.
  • Be patient and gentle. Your body defends its weight. Slow and sustainable beats fast and strict.
  • Health is more than the scales. Getting stronger, sleeping better, being fitter — these are gains the number doesn’t always show.

In closing

If you’ve ever felt you failed because a diet didn’t “take,” I want you to take this with you: you didn’t fail. You were fighting a body programmed to protect you, often with rules that were never meant to be kept up. That isn’t weakness. That’s being human.

Science gives you no miracle cure. But it gives you something better: permission to stop fighting yourself, and to start with something you actually can carry.

What is one small, sustainable change that — a year from now — you’ll still see yourself doing?

Related reading


Important: this article shares general science, not personal medical or nutritional advice. If you want to lose weight, have health complaints, or have something going on with hormones, thyroid or medication, do discuss it with your GP or a dietitian. They can look at your situation — a blog cannot.


Sources

  • Sumithran P, Prendergast LA, Delbridge E, et al. Long-term persistence of hormonal adaptations to weight loss. NEJM. 2011;365(17):1597–1604. https://doi.org/10.1056/NEJMoa1105816
  • MacLean PS, Bergouignan A, Cornier MA, Jackman MR. Biology’s response to dieting: the impetus for weight regain. Am J Physiol Regul Integr Comp Physiol. 2011;301(3):R581–R600. https://doi.org/10.1152/ajpregu.00755.2010
  • Pontzer H, Yamada Y, Sagayama H, et al. Daily energy expenditure through the human life course. Science. 2021;373(6556):808–812. https://doi.org/10.1126/science.abe5017
  • Greendale GA, Sternfeld B, Huang M, et al. Changes in body composition and weight during the menopause transition. JCI Insight. 2019;4(5):e124865. https://doi.org/10.1172/jci.insight.124865
  • Gardner CD, Trepanowski JF, Del Gobbo LC, et al. Effect of low-fat vs low-carbohydrate diet on 12-month weight loss (DIETFITS). JAMA. 2018;319(7):667–679. https://doi.org/10.1001/jama.2018.0245
  • Lowe DA, Wu N, Rohdin-Bibby L, et al. Effects of time-restricted eating on weight loss and other metabolic parameters (TREAT). JAMA Internal Medicine. 2020;180(11):1491–1499. https://doi.org/10.1001/jamainternmed.2020.4153
  • Zhang Q, Zhang C, Wang H, et al. Intermittent fasting versus continuous calorie restriction: which is better for weight loss? Nutrients. 2022;14(9):1781. https://doi.org/10.3390/nu14091781
  • Semnani-Azad Z, Khan TA, Chiavaroli L, et al. Intermittent fasting strategies and their effects on body weight and other cardiometabolic risk factors: systematic review and network meta-analysis of randomised clinical trials. BMJ. 2025;389:e082007. https://doi.org/10.1136/bmj-2024-082007
  • Wu X, Ding Y, Cao Q, et al. Comparison of different intermittent fasting patterns or different extents of calorie restriction for weight loss and metabolic improvement in adults: a systematic review and network meta-analysis of randomised controlled trials. Nutrition Reviews. Advance online publication, 14 May 2025. https://doi.org/10.1093/nutrit/nuaf056

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